Susceptibility to chronic inflammatory diseases, such as atopic dermatitis or psoriasis, can be determined with the help of genetic testing. Tests are aimed at examining the polymorphism of the genes responsible for the reactivity of the immune system. In addition to the susceptibility to a disease, this study helps to get information about the sensitivity of the skin and its susceptibility to inflammatory processes and scarring and predict the speed of regeneration.
These polymorphisms affect the response of the skin to many products we use in everyday life – from deodorants and detergents to air fresheners. Contacts with these products may lead to chronic irritation and persistent skin redness.
However, in addition to getting information about possible reactions to household irritants, genetic testing also helps to know detect the risks of inflammatory complications after certain cosmetic procedures, which has great practical value for dermatologists and cosmetologists. Mesotherapy, chemical peels, laser skin resurfacing can cause a long-lasting inflammatory reaction in patients with polymorphisms of certain genes. The consequences of such a reaction include not only persistent redness, but also the formation of scars, the appearance of unwanted pigmentation, and even infectious processes.
Having the information based on genetic testing, the specialist will be able to select more benign procedures (for example, peels with partially neutralized acids) and suitable after-treatment care products containing antioxidants and herbal ingredients that can arrest inflammatory processes. It also helps to choose the appropriate nutricosmetics – that is, dietary supplements that will help the body from the inside. At the same time, in order to make a correct diagnosis, it is important to examine not only polymorphisms in the reactivity genes of the immune system, but other possible features as well: polymorphisms in groups of genes responsible for the body’s response to oxidative stress, as well as biotransformation system genes.