Papers of the Month: February, 2013
Novel Genital Alphapapillomaviruses in Baboons (Papio hamadryas Anubis) With Cervical Dysplasia
Vet. Pathol. 2013 Jan;50(1):200-8.
Comments by Dr. Murray Gardner:
Always of interest is the discovery of a naturally occurring animal model of human disease ,Such an example is published in the latest issue of Veterinary Pathology ( 50:200-208, Jan.2013). The authors describe a novel genital papillomavirus infection associated with cervical dysplasia in baboons. The virus is closely related to the oncogenic alpha papillomaviruses that infect humans and macaques. The viruses were detected in 6 of 15 wild –caught Kenyan olive baboons that were in an experimental study of cervical Chlamydia trachomatis infection. In 3 of the animals the lesions were consistent with cervical squamous intraepithelial neoplasia.This unexpected finding represents yet another valuable animal model of human disease.
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