Comparative Pathology: Hereditary Multiple Exostosis

Chondrosarcomas occur in mice with conditional inactivation of the gene, exostoses (multiple) 1 (Ext1) and in some varieties of CD1 and NOD mice. This image shows a tibial lesion with ample chondroblasts.

Chondrosarcoma (Mouse)

 

 

Click here to see the whole slide image.

Click here to view the human pathology.

 

Reference:

Kavirayani AM, Sundberg JP, Foreman O. Primary Neoplasms of Bones in Mice: Retrospective Study and Review of Literature. Vet Pathol. 2011 Feb 22. [Epub ahead of print] PubMed PMID: 21343597; PubMed Central PMCID: PMC3151475.

 

 

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