A 58 year old male presents with chief complaints of bloating, vague abdominal pain and dark black stools. He is referred to a gastroenterologist who recommends upper and lower endoscopy. Subsequently a mass of about 11×12 mm is removed from the stomach.
Review first the H&E stained image below. The most likely diagnosis is:
- Desmoid tumor
- Inflammatory fibroid polyp
- Gastrointestinal stromal tumor
What immunohistochemical or gene expression tests would you order to confirm the diagnosis?
- CD 117 (c-kit)
- All of the above
- None of the above
Laurini JA and Carter JE, Gastrointestinal stromal tumors: A review of the literature, Archives of Pathology and Laboratory Medicine 134:pp134-141, 2010.
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