Nature. 2011 Feb 17;470(7334):409-13.
CKIα ablation highlights a critical role for p53 in invasiveness control.
Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y.
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Ko mice continue to illuminate the molecular pathways to colon ca. Critical role of p53 fits nicely with Volgelstein’s stepwise model of colon carcinogenesis.